Ranking Profile - Homology Medicines Inc

Introduction

Homology Medicines Inc (Homology) is a genetic medicines company that discovers and develops gene therapies to treat genetic disorders. The company is investigating pipeline programs HMI-102, a gene therapy for the treatment of phenylketonuria (PKU); and HMI-202, an investigational gene therapy targeting metachromatic leukodystrophy. It is also evaluating HMI-103, an investigational gene editing program for the treatment of pediatric phenylketonuria, and HMI-203, an investigational gene therapy for the treatment of Hunter syndrome. Homology gene-editing technology is used in DNA repairs, and gene therapy approach along with AAVHSC vectors delivers a functional gene to treat monogenic diseases in the liver, lung, none marrow and eye. Homology is headquartered in Bedford, Massachusetts, the US.